Chelsea D Frost

Chelsea D Frost, MD


Business Phone: (352) 273-9860
Business Email:

About Chelsea D Frost

My name is Chelsea Frost, MD, MS, and I am a board-certified physical medicine and rehabilitation physician and an assistant professor in the University of Florida Department of Physical Medicine and Rehabilitation. I received my undergraduate degree from the University of South Florida as well as my master’s degree and medical degree from USF Health Morsani College of Medicine. Following medical school, I moved to Charlottesville, Virginia, where I completed my residency in physical medicine and rehabilitation at the University of Virginia. I then completed a fellowship in interventional spine and musculoskeletal medicine at Emory University. Prior to joining UF Health, I served as an assistant professor at USF Health Morsani, where I practiced interventional pain management at Tampa General Hospital.

As a physician, my goal is to work together with my patients to develop a treatment plan that gets them back to their functional goals regarding their spine and musculoskeletal health. I encourage my patients to ask questions to feel fully informed of their own health care. I work comprehensively with my patients to assess their current functional status and goals, and then develop a treatment plan that will help get them back to those activities they love. I have a holistic approach to patient care and fully encourage my patients to be active participants in their health plan. Treatment recommendations can include physical therapy, mindfulness exercises, non-opioid medications and interventional procedures.

My clinical interests include spine and musculoskeletal care, as well as whole-body wellness. I have treated a vast array of athletes — from the weekend warrior to professional players — in addition to non-athletes, to help them achieve their goals and return to their favorite activities. I enjoy helping patients to start moving and to keep moving to maintain their desired active lifestyles.

In my free time, I enjoy spending time with my husband and rescue pups, and we can often be found on a hiking trail. I also enjoy cooking, weightlifting, running and swimming. I previously swam in high school and on the USF intercollegiate club team throughout college.

Board Certifications

  • Physical Medicine and Rehabilitation
    American Board of Physical Medicine and Rehabilitation

Clinical Profile

  • Physical Medicine and Rehabilitation
Areas of Interest
  • Back pain – when you see the doctor
  • Cervical Spondylosis
  • Epidural injections for back pain
  • Exercise and age
  • Herniated disk
  • Hip joint injection
  • Hip pain
  • Knee pain
  • Low back pain – acute
  • Low back pain – chronic
  • Medicines for back pain
  • Muscle strain treatment
  • Neck pain
  • Osteoarthritis
  • Sciatica
  • Scoliosis
  • Spinal stenosis
  • Tailbone trauma


Botulinum Toxin Injections for Muscle Spasticity
Bedside Pain Management Interventions. 641-663 [DOI] 10.1007/978-3-031-11188-4_61.
Spine Injury Prevention.
Clinics in sports medicine. 40(3):429-444 [DOI] 10.1016/j.csm.2021.03.001. [PMID] 34051938.
Spontaneous regression of a foraminal discal cyst: Case report
American Journal of Physical Medicine & Rehabilitation. 100(4):a122-a122 [DOI] 10.1097/phm.0000000000001696.
A rare occurrence of singultus following lumbar interlaminar epidural steroid injection: A case report
American Journal of Physical Medicine & Rehabilitation. 99(3S):a263-a263 [DOI] 10.1097/phm.0000000000001387.
Publication Rate of Podium Presentations From the North American Spine Society Annual Meetings
Global Spine Journal. 8(3):273-278 [DOI] 10.1177/2192568217713732. [PMID] 29796376.
Online Reviews of Orthopedic Surgeons: An Emerging Trend
Orthopedics. 38(4):e257-62 [DOI] 10.3928/01477447-20150402-52. [PMID] 25901617.
Publication rate of paper presentations from the Cervical Spine Research Society annual meeting.
Spine. 40(10):699-702 [DOI] 10.1097/BRS.0000000000000838. [PMID] 25705960.
The Publication Rate of Presentations at Two International Spine Meetings: Scoliosis Research Society and International Meeting of Advanced Spinal Techniques.
Spine deformity. 3(6):528-532 [DOI] 10.1016/j.jspd.2015.04.009. [PMID] 27927554.
Upper Cervical Epidural Abscess in a Patient With Parkinson Disease
Geriatric Orthopaedic Surgery & Rehabilitation. 6(4):328-333 [DOI] 10.1177/2151458515604356. [PMID] 26623170.
Butterfly vertebra mimicking a compression fracture.
The spine journal : official journal of the North American Spine Society. 14(10):2509-10 [DOI] 10.1016/j.spinee.2014.05.009. [PMID] 24846847.
Cardiac hormones target nuclear oncogenes c-Fos and c-Jun in carcinoma cells.
European journal of clinical investigation. 43(11):1156-62 [DOI] 10.1111/eci.12153. [PMID] 23992401.
Cardiac hormones are c-Jun-N-terminal kinase 2-inhibiting peptides.
Anticancer research. 32(3):721-5 [PMID] 22399583.
Novel dual inhibitors of vascular endothelial growth factor and VEGFR2 receptor.
European journal of clinical investigation. 42(10):1061-7 [DOI] 10.1111/j.1365-2362.2012.02695.x. [PMID] 22703300.
Potent selective inhibition of STAT 3 versus STAT 1 by cardiac hormones.
Molecular and cellular biochemistry. 371(1-2):209-15 [DOI] 10.1007/s11010-012-1437-1. [PMID] 22965761.


Fellowship, Interventional Spine and Musculoskeletal Medicine
2020-2021 · Emory University
Chief Resident, Physical Medicine and Rehabilitation
2019-2020 · University of Virginia
Residency, Physical Medicine and Rehabilitation
2016-2020 · University of Virginia
Medical School
2012-2016 · University of South Florida

Contact Details

(352) 273-9860
Business Mailing:
PO Box 112730
3450 HULL RD
Business Street:
PO Box 112730
3450 HULL RD