Disease Course of Osteoarthritis: Exercise and Pharmacological Interventions

Our team is actively involved in advancing knowledge of the interactions of single and multiple joint osteoarthritis (OA) on patient-centered outcomes, function and quality of life. With our expertise in ‘exercise is medicine’, we have studied different resistance training protocols to improve joint function, functional joint pain and biologic markers of OA over time. We are also generating publications using data from the Osteoarthritis Initiative to understand the effects of knee, spine and hip OA on physical measures, depression and ability to participate in life activities. Finally, the use of various non-surgical treatments has been published. Some of this research has been funded through NIH NIAMS.

Recent publications related to these topics:

Concentric and Eccentric Resistance Training Comparison on Physical Function and Functional Pain Outcomes in Knee Osteoarthritis: A Randomized Controlled Trial. Vincent KR, Vincent HK. Am J Phys Med Rehabil. 2020;99(10):932-940. 

Exercise Prescription for Weight Management in Obese Adults at Risk for Osteoarthritis: Synthesis From a Systematic Review.  Barrow DR, Abbate LM, Paquette MR, Driban JB,  Vincent HK, Newman C,  Messier SP,Ambrose KR, Shultz SP. BMC Musculoskelet Disord. 2019 Dec 20;20(1):610.

AAOS Appropriate Use Criteria: Optimizing the Non-Arthroplasty Management of Osteoarthritis of the Knee. Yates AJ Jr, McGrory BJ, Starz TW, Vincent KR, McCardel B, Golightly YM. J Am Acad Orthop Surg. 2014 Apr;22(4):261-7.

Eccentric and Concentric Resistance Exercise Comparison for Knee Osteoarthritis. Vincent KR, Vasilopoulos T, Montero C, Vincent HK. Med Sci Sports Exerc. 2019 Oct;51(10):1977-1986.

Managing Osteoarthritis and Other Chronic Musculoskeletal Pain Disorders. Dubin AH. Med Clin North Am. 2016 Jan;100(1):143-50.