Stroke and Traumatic Brain Injury

Dr. Geis, the PMR research team and medical students supervise a gait session with an individual undergoing treatment for spasticity.

Our faculty are working to optimize therapeutic pathways for patients with stroke and traumatic brain injury. Investigations focus on methods of reducing lower limb spasticity in patients with chronic stroke with the intent of improving mobility and function. Ongoing research includes determination of biomechanical gait changes with Botulinum injections in the lower extremity.

Publications related to these topics:

Impact of early intervention with onabotulinumtoxinA treatment in adult patients with post-stroke lower limb spasticity: results from the double-blind, placebo-controlled, phase 3 REFLEX study. Patel AT, Ward AB, Geis C, Jost WH, Liu C, Dimitrova R. J Neural Transm (Vienna). 2020 Dec;127(12):1619-1629.

Optimal Muscle Selection for OnabotulinumtoxinA Injections in Poststroke Lower-Limb Spasticity: A Randomized Trial. Esquenazi A, Wein TH, Ward AB, Geis C, Liu C, Dimitrova R. Am J Phys Med Rehabil.  2019 May;98(5):360-368.

Long-Term Follow-up to a Randomized Controlled Trial Comparing Peroneal Nerve Functional Electrical Stimulation to an Ankle Foot Orthosis for Patients With Chronic Stroke.  Rogers HL, Nolan KJ, Abrams GM, Annaswamy T,  Brandstater M, Browne B,  Burnfield JM,  Feng W,  Freed MJ, Geis C, Greenberg J, Gudesblatt M, Ikramuddin F, Jayaraman A, Kautz SA, Lutsep HL, Madhavan S, Meilahn J, Pease WS, Rao N, Seetharama S, Sethi P, Turk MA, Wallis RA,  Kufta C. Neurorehabil Neural Repair. Nov-Dec 2015;29(10):911-22.